Well, we are currently big-paw less, but we drive a Nissan Pathfinder and love it. Izzy was also a big fan. The backseat was plenty big enough for his furry lumpy self, though his favorite spot was to lay in between the back and front seats on the floor.
Go figure.
But, the quick run down: Good gas mileage for an SUV (18MPG average, and I drive crazy mountain roads), very comfortable drive with lots of pep and very responsive steering. No mechanical problems thus far (we've only had it a year and it has 80k on it, bought used for a great price), attractive car, eays to maneuver as it's small outside but big inside, lots of storage in back, front, etc. Lots of leg room, and head room, seats 5 adults comfortably, carseats are easy to get into and out of (I don't need them, but I had to do it once) upholstery is low maintenance, great AC and heating, good sound system. And, not that most people would need this as a consideration, but if you are driving in snow this car ROCKS. I drove in snow up to the grill almost everyday for two months and only got stuck once.
Now for the doggy bits: The backseat can be a little difficult to maneuver into, but Iz got great at putting a paw onto to stepbar and hoisting himself in. Getting into the back hatch was very easy. COuld have easily fit two newfs in the back, but one was very comfy on the backseat. Cleaning inside was simple, and we kept an office mat (you know the plastic thing under office chairs to protect carpet) on the floor of the back trunk space for when he got messy/wet, etc.
Overall, I can't see myself driving anything else anymore. I'm in love.