Congratulation s on your new addition. I would say to not feed her before the trip but I don't know how long before would be ok since she is so young. When I got Gabriel in March, he was 6 weeks old and the trip home was 4 1/2 hours. I put him in the kennel cab and when he cried, I would put my hand at the door. He did really well. He was at Animal Control and although they knew I was coming, they let him eat. Poor boy, he threw up twice on the way home. I brought towels, a bowl for water, and waterless shampoo. We stopped a couple of times, about every hour and a half. But that was just me.